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Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant

A synthetic heroin analog (MorHap) and a synthetic 42 amino acid V2 loop peptide from A/E strain of HIV-1 gp120 envelope protein that was previously used in a successful phase III vaccine trial were constructed as antigens together with liposomes containing monophosphoryl lipid A as an adjuvant, to...

詳細記述

保存先:
書誌詳細
出版年:NPJ Vaccines
主要な著者: Torres, Oscar B., Matyas, Gary R., Rao, Mangala, Peachman, Kristina K., Jalah, Rashmi, Beck, Zoltan, Michael, Nelson L., Rice, Kenner C., Jacobson, Arthur E., Alving, Carl R.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604742/
https://ncbi.nlm.nih.gov/pubmed/29263870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0013-9
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