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Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome
Aircrew complain of illness following a fume event in aircraft. A chemical in jet engine oil, the neurotoxicant, tri-o-cresyl phosphate, after metabolic activation to cresyl saligenin phosphate, makes a covalent adduct on butyrylcholinesterase (BChE). We developed a mass spectrometry method for dete...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119843/ https://ncbi.nlm.nih.gov/pubmed/24892986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.05.021 |
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