Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome

Aircrew complain of illness following a fume event in aircraft. A chemical in jet engine oil, the neurotoxicant, tri-o-cresyl phosphate, after metabolic activation to cresyl saligenin phosphate, makes a covalent adduct on butyrylcholinesterase (BChE). We developed a mass spectrometry method for dete...

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Hlavní autoři: Schopfer, Lawrence M., Masson, Patrick, Lamourette, Patricia, Simon, Stéphanie, Lockridge, Oksana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119843/
https://ncbi.nlm.nih.gov/pubmed/24892986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.05.021
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