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By Hook or by Crook: Multifaceted DNA-Binding Properties of MeCP2
Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interac...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119793/ https://ncbi.nlm.nih.gov/pubmed/23452844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.017 |
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