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By Hook or by Crook: Multifaceted DNA-Binding Properties of MeCP2

Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in chromatin organization and clinical features of Rett syndrome. Mellén et al. find the methyl-CpG-binding domain of MeCP2 interac...

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Bibliografische gegevens
Hoofdauteurs: Shin, Jaehoon, Ming, Guo-li, Song, Hongjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119793/
https://ncbi.nlm.nih.gov/pubmed/23452844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.02.017
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