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MeCP2: multifaceted roles in gene regulation and neural development

Methyl-CpG-binding protein 2 (MeCP2) is a classic methylated-DNA-binding protein, dysfunctions of which lead to various neurodevelopmental disorders such as Rett syndrome and autism spectrum disorder. Initially recognized as a transcriptional repressor, MeCP2 has been studied extensively and its fun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurosci Bull
Hauptverfasser: Cheng, Tian-Lin, Qiu, Zilong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562630/
https://ncbi.nlm.nih.gov/pubmed/25082535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-014-1452-6
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