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The role of MeCP2 in CNS development and function

Rett syndrome is a neurodevelopmental disorder that is a direct consequence of functional mutations in the methyl-CpG-binding protein-2 (MeCP2) gene, which has focused attention on epigenetic mechanisms in neurons. MeCP2 is widely believed to be a transcriptional repressor although it may have addit...

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Detalhes bibliográficos
Main Authors: Na, Elisa S., Monteggia, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077534/
https://ncbi.nlm.nih.gov/pubmed/20515694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2010.05.014
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