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The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator of gene expression that is an important epigenetic factor in the maintenance and development of the central nervous system. The neurodevelopmental disorders Rett syndrome and MECP2 duplication syndrome arise from loss-of-function an...

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Detalhes bibliográficos
Main Authors: Na, Elisa S, Nelson, Erika D, Kavalali, Ege T, Monteggia, Lisa M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521965/
https://ncbi.nlm.nih.gov/pubmed/22781840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.116
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