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The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator of gene expression that is an important epigenetic factor in the maintenance and development of the central nervous system. The neurodevelopmental disorders Rett syndrome and MECP2 duplication syndrome arise from loss-of-function an...

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Détails bibliographiques
Auteurs principaux: Na, Elisa S, Nelson, Erika D, Kavalali, Ege T, Monteggia, Lisa M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521965/
https://ncbi.nlm.nih.gov/pubmed/22781840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.116
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