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The Role of MeCP2 in Brain Development and Neurodevelopmental Disorders

Methyl CpG binding protein-2 (MeCP2) is an essential epigenetic regulator in human brain development. Rett syndrome, the primary disorder caused by mutations in the X-linked MECP2 gene, is characterized by a period of cognitive decline and development of hand stereotypies and seizures following an a...

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Bibliografiske detaljer
Main Authors: Gonzales, Michael L., LaSalle, Janine M.
Format: Artigo
Sprog:Inglês
Udgivet: Current Science Inc. 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847695/
https://ncbi.nlm.nih.gov/pubmed/20425298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11920-010-0097-7
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