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MeCP2 as an activator of gene expression

Rett Syndrome is a neurodevelopmental disorder that primarily affects females and is caused by mutations in the methyl-CpG-binding-protein 2 (MeCP2) gene. Initially, MeCP2 had been shown to be a repressor of gene transcription. In their 2008 paper, Chahrour and colleagues (DOI: 10.1126/science.11532...

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Detalhes bibliográficos
Publicado no:Trends Neurosci
Main Authors: Horvath, Patricia M., Monteggia, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909705/
https://ncbi.nlm.nih.gov/pubmed/29405930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2017.11.005
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