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Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs
MeCP2 encodes a methyl-CpG-binding protein that plays a critical role in repressing gene expression, mutations of which lead to Rett syndrome and autism. PTEN is a critical tumor suppressor gene that is frequently mutated in human cancers and autism spectrum disorders. Various studies have shown tha...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4740767/ https://ncbi.nlm.nih.gov/pubmed/26843422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20392 |
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