MicroRNA-197 controls ADAM10 expression to mediate MeCP2’s role in the differentiation of neuronal progenitors

Duplication of MECP2 (Methyl-CpG-binding protein 2) causes severe mental illness called MECP2 duplication syndrome (MDS), yet the underlying mechanism remains elusive. Here we show, in Tg(MECP2) transgenic mouse brain or cultured neural progenitor cells (NPCs), that elevated MeCP2 expression promote...

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Publicado en:Cell Death Differ
Autores principales: Wang, Yu-Meng, Zheng, Yu-Fang, Yang, Si-Yu, Yang, Zhang-Min, Zhang, Lin-Na, He, Yan-Qin, Gong, Xiao-Hong, Liu, Dong, Finnell, Richard H., Qiu, Zi-Long, Du, Ya-Song, Wang, Hong-Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748079/
https://ncbi.nlm.nih.gov/pubmed/30560934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0257-6
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