MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity

Nerve injury induces chronic pain and dysregulation of microRNAs in dorsal root ganglia (DRG). Several downregulated microRNAs are predicted to target Mecp2. MECP2 mutations cause Rett syndrome and these patients report decreased pain perception. We confirmed MeCP2 upregulation in DRG following nerv...

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Dettagli Bibliografici
Pubblicato in:FEBS Open Bio
Autori principali: Manners, Melissa T., Tian, Yuzhen, Zhou, Zhaolan, Ajit, Seena K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571540/
https://ncbi.nlm.nih.gov/pubmed/26448907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.010
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