MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity

Nerve injury induces chronic pain and dysregulation of microRNAs in dorsal root ganglia (DRG). Several downregulated microRNAs are predicted to target Mecp2. MECP2 mutations cause Rett syndrome and these patients report decreased pain perception. We confirmed MeCP2 upregulation in DRG following nerv...

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Sparad:
Bibliografiska uppgifter
I publikationen:FEBS Open Bio
Huvudupphovsmän: Manners, Melissa T., Tian, Yuzhen, Zhou, Zhaolan, Ajit, Seena K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2015
Ämnen:
Research article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571540/
https://ncbi.nlm.nih.gov/pubmed/26448907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.010
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