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MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity

Nerve injury induces chronic pain and dysregulation of microRNAs in dorsal root ganglia (DRG). Several downregulated microRNAs are predicted to target Mecp2. MECP2 mutations cause Rett syndrome and these patients report decreased pain perception. We confirmed MeCP2 upregulation in DRG following nerv...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Manners, Melissa T., Tian, Yuzhen, Zhou, Zhaolan, Ajit, Seena K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571540/
https://ncbi.nlm.nih.gov/pubmed/26448907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.010
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