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MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

The X-linked transcriptional repressor methyl CpG binding protein 2 (MeCP2), known for its role in the neurodevelopmental disorder Rett syndrome, is emerging as an important regulator of neuroplasticity in post-mitotic neurons. Cocaine addiction is commonly viewed as a disorder of neuroplasticity, b...

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Bibliographic Details
Main Authors: Im, Heh-In, Hollander, Jonathan A., Bali, Purva, Kenny, Paul J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928848/
https://ncbi.nlm.nih.gov/pubmed/20711185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2615
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