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Combination therapy with anti-DR5 antibody and tamoxifen for triple negative breast cancer
TRA-8, a monoclonal antibody targeting death receptor, has demonstrated high therapeutic effect for triple negative breast cancer (TNBC) in preclinical models. Tamoxifen, the standard of care for ERα-positive breast cancer, induces apoptosis via ERβ, which commonly presents in TNBC cells. The curren...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119072/ https://ncbi.nlm.nih.gov/pubmed/25084100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29183 |
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