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Diffusion Weighted Imaging Evaluated the Early Therapy Effect of Tamoxifen in an MNU-Induced Mammary Cancer Rat Model

PURPOSE: To assess the optimal time point of diffusion-weighted imaging (DWI) for early prognosis of breast cancer following tamoxifen therapy using a methylnitrosourea (MNU)-induced ER-positive breast-cancer model. METHODS: Two groups of Sprague-Dawley rats (n = 15 for group 1; n = 10 for group 2)...

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Main Authors: Zhai, Guihua, Grubbs, Clinton J., Stockard, Cecil R., Umphrey, Heidi R., Beasley, T. Mark, Kim, Hyunki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660312/
https://ncbi.nlm.nih.gov/pubmed/23700476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064445
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