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Early Therapy Assessment of Combined Anti-DR5 Antibody and Carboplatin in Triple-Negative Breast Cancer Xenografts in Mice Using Diffusion-Weighted Imaging and (1)H MR Spectroscopy

PURPOSE: To assess the early response of triple-negative breast-cancer (TNBC) following TRA-8 and carboplatin therapy using DWI and MRS in 2LMP and SUM159 mouse models. MATERIALS AND METHODS: Four groups (n = 5/group) of each model were untreated or treated with carboplatin, TRA-8, and combination,...

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Detalhes bibliográficos
Main Authors: Zhai, Guihua, Kim, Hyunki, Sarver, David, Samuel, Sharon, Whitworth, Lee, Umphrey, Heidi, Oelschlager, Denise K., Beasley, T. Mark, Zinn, Kurt R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076049/
https://ncbi.nlm.nih.gov/pubmed/24151215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.24319
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