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Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma

The study goal was to assess the efficacy of combined EMMPRIN and DR5 targeted therapy for pancreatic adenocarcinoma in orthotopic mouse models using multi-modal imaging. Cytotoxicity of anti-EMMPRIN antibody and anti-DR5 antibody (TRA-8) in MIA PaCa-2 and PANC-1 cell lines was measured by ATPlite a...

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Detalhes bibliográficos
Main Authors: Kim, Hyunki, Zhai, Guihua, Samuel, Sharon L., Rigell, Christopher J., Umphrey, Heidi R., Rana, Samir, Stockard, Cecil R., Fineberg, Naomi S., Zinn, Kurt R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277644/
https://ncbi.nlm.nih.gov/pubmed/22203731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0581
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