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Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma

The study goal was to assess the efficacy of combined EMMPRIN and DR5 targeted therapy for pancreatic adenocarcinoma in orthotopic mouse models using multi-modal imaging. Cytotoxicity of anti-EMMPRIN antibody and anti-DR5 antibody (TRA-8) in MIA PaCa-2 and PANC-1 cell lines was measured by ATPlite a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hyunki, Zhai, Guihua, Samuel, Sharon L., Rigell, Christopher J., Umphrey, Heidi R., Rana, Samir, Stockard, Cecil R., Fineberg, Naomi S., Zinn, Kurt R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277644/
https://ncbi.nlm.nih.gov/pubmed/22203731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0581
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