p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Increased expression of wild-type p53 in response to DNA damage arrests cells late in the G1 stage of the cell cycle by stimulating the synthesis of inhibitors of cyclin-dependent kinases, such as p21/WAF1. To study the effects of p53 without the complication of DNA damage, we used tetracycline to r...

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Detaylı Bibliyografya
Asıl Yazarlar: Agarwal, M L, Agarwal, A, Taylor, W R, Stark, G R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC41183/
https://ncbi.nlm.nih.gov/pubmed/7667317
Etiketler: Etiketle
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