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Sphingosine, a Modulator of Human Translesion DNA Polymerase Activity
Translesion (TLS) DNA polymerases are specialized, error-prone enzymes that synthesize DNA across bulky, replication-stalling DNA adducts. In so doing, they facilitate the progression of DNA synthesis and promote cell proliferation. To potentiate the effect of cancer chemotherapeutic regimens, we so...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118125/ https://ncbi.nlm.nih.gov/pubmed/24928506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570242 |
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