A Role for Rab7 in the Movement of Secretory Granules in Cytotoxic T Lymphocytes

Cytotoxic T lymphocytes (CTL) are potent killers of virally infected and tumorigenic cells. Upon recognition of target cells, CTL undergo polarized secretion of secretory lysosomes at the immunological synapse (IS) that forms between CTL and target. However, the molecular machinery involved in the p...

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Bibliographische Detailangaben
Hauptverfasser: Daniele, Tiziana, Hackmann, Yvonne, Ritter, Alex T., Wenham, Matt, Booth, Sarah, Bossi, Giovanna, Schintler, Michael, Auer-Grumbach, Michaela, Griffiths, Gillian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116565/
https://ncbi.nlm.nih.gov/pubmed/21438969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01194.x
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