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Rab3D Is Critical for Secretory Granule Maturation in PC12 Cells
Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex. This maturation process is characterized by acidification-dependent processing of cargo...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602456/ https://ncbi.nlm.nih.gov/pubmed/23526941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057321 |
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