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A Role for Rab7 in the Movement of Secretory Granules in Cytotoxic T Lymphocytes

Cytotoxic T lymphocytes (CTL) are potent killers of virally infected and tumorigenic cells. Upon recognition of target cells, CTL undergo polarized secretion of secretory lysosomes at the immunological synapse (IS) that forms between CTL and target. However, the molecular machinery involved in the p...

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Detalhes bibliográficos
Main Authors: Daniele, Tiziana, Hackmann, Yvonne, Ritter, Alex T., Wenham, Matt, Booth, Sarah, Bossi, Giovanna, Schintler, Michael, Auer-Grumbach, Michaela, Griffiths, Gillian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116565/
https://ncbi.nlm.nih.gov/pubmed/21438969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01194.x
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