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A Role for Rab7 in the Movement of Secretory Granules in Cytotoxic T Lymphocytes

Cytotoxic T lymphocytes (CTL) are potent killers of virally infected and tumorigenic cells. Upon recognition of target cells, CTL undergo polarized secretion of secretory lysosomes at the immunological synapse (IS) that forms between CTL and target. However, the molecular machinery involved in the p...

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Dettagli Bibliografici
Autori principali: Daniele, Tiziana, Hackmann, Yvonne, Ritter, Alex T., Wenham, Matt, Booth, Sarah, Bossi, Giovanna, Schintler, Michael, Auer-Grumbach, Michaela, Griffiths, Gillian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116565/
https://ncbi.nlm.nih.gov/pubmed/21438969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2011.01194.x
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