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Decreased Proteasomal Activity Causes Photoreceptor Degeneration in Mice
PURPOSE. To study the retinal degeneration caused by decreased proteasomal activity in β5t transgenic (β5t-Tg) mice, an animal model of senescence acceleration. METHODS. β5t-Tg mice and age-matched littermate control (WT) mice were used. Proteasomal activities and protein level of poly-ubiquitinated...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116152/ https://ncbi.nlm.nih.gov/pubmed/24994871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13272 |
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