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TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane

The epithelial-mesenchymal transition (EMT) is a key process in fibrogenic diseases where transdifferentiated myofibroblasts produce excessive amounts of extracellular matrix, resulting in organ dysfunction. Idiopathic epiretinal membrane (iERM) is a vision-threatening disorder characterized by fibr...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kanda, Atsuhiro, Noda, Kousuke, Hirose, Ikuyo, Ishida, Susumu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346093/
https://ncbi.nlm.nih.gov/pubmed/30679596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36917-9
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