EEF1A2 inactivates p53 via PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

Mouse Double Minute homolog 4 (MDM4) gene upregulation often occurs in human hepatocellular carcinoma (HCC), but the molecular mechanisms responsible for its induction remain poorly understood. Here, we investigated the role of the phosphoinositide-3-kinase/v-akt murine thymoma viral oncogene homolo...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Pellegrino, Rossella, Calvisi, Diego F., Neumann, Olaf, Kolluru, Venkatesh, Wesely, Josephine, Chen, Xin, Wang, Chunmei, Wuestefeld, Torsten, Ladu, Sara, Elgohary, Nahla, Bermejo, Justo Lorenzo, Radlwimmer, Bernhard, Zörnig, Martin, Zender, Lars, Dombrowski, Frank, Evert, Matthias, Schirmacher, Peter, Longerich, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115286/
https://ncbi.nlm.nih.gov/pubmed/24285179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26954
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller