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NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

The mitochondrial matrix GTPase NOA1 is a nuclear encoded protein, essential for mitochondrial protein synthesis, oxidative phosphorylation and ATP production. Here, we demonstrate that newly translated NOA1 protein is imported into the nucleus, where it localizes to the nucleolus and interacts with...

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Detalles Bibliográficos
Main Authors: Al-Furoukh, Natalie, Kardon, Julia R., Krüger, Marcus, Szibor, Marten, Baker, Tania A., Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114565/
https://ncbi.nlm.nih.gov/pubmed/25072814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103141
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