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NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

The mitochondrial matrix GTPase NOA1 is a nuclear encoded protein, essential for mitochondrial protein synthesis, oxidative phosphorylation and ATP production. Here, we demonstrate that newly translated NOA1 protein is imported into the nucleus, where it localizes to the nucleolus and interacts with...

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Detalhes bibliográficos
Main Authors: Al-Furoukh, Natalie, Kardon, Julia R., Krüger, Marcus, Szibor, Marten, Baker, Tania A., Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114565/
https://ncbi.nlm.nih.gov/pubmed/25072814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103141
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