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IRAK-M Deficiency Promotes the Development of Type 1 Diabetes in NOD Mice
Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by progressive destruction of insulin-secreting pancreatic β-cells. Both T-cell–mediated adaptive responses as well as innate immune processes are involved in pathogenesis. Interleukin-1 receptor–associated kinase...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113073/ https://ncbi.nlm.nih.gov/pubmed/24696448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1504 |
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