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Activation-induced cytidine deaminase deficiency accelerates autoimmune diabetes in NOD mice
B cells play an important role in type 1 diabetes (T1D) development. However, the role of B cell activation-induced cytidine deaminase (AID) in diabetes development is not clear. We hypothesized that AID is important in the immunopathogenesis of T1D. To test this hypothesis, we generated AID-deficie...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5821212/ https://ncbi.nlm.nih.gov/pubmed/29321370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95882 |
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