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TLR9 deficiency promotes CD73 expression in T cells and diabetes protection in NOD mice
TLR9-/-NOD mice develop a significantly reduced incidence of diabetes. This study was to investigate the molecular mechanisms of the protective role of TLR9 deficiency. Through gene screening and confirmation by both mRNA and protein expression, we found a significant increase in CD73-expressing imm...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788667/ https://ncbi.nlm.nih.gov/pubmed/23956420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300547 |
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