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The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes
Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of the insulin-producing pancreatic β cells. A combination of genetic and environmental factors eventually leads to the loss of functional β cells mass and hyperglycemia. Both innate and adapti...
Enregistré dans:
| Publié dans: | J Autoimmun |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4903935/ https://ncbi.nlm.nih.gov/pubmed/27021275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.03.006 |
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