Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus

VN/14-1 [4-(±)-(1H-Imidazol-1-yl)-(E)-retinoic acid], a novel retinoic acid metabolism blocking agent (RAMBA), works by inhibiting the breakdown of all-trans-retinoic acid. The purpose of this study was to evaluate the anti-tumor effects of VN/14-1 on the N-methyl-N-nitrosourea (MNU)-induced rat mam...

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Main Authors: Goss, Paul E., Qi, Shangle, Hu, Haiqing, Gediya, Lalji K., Purushottamachar, Puranik, Godbole, Abhijit M., Njar, Vincent C. O.
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112508/
https://ncbi.nlm.nih.gov/pubmed/21842418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1724-7
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