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Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea (MNU)-induced mammary carcinoma and uterus in the rat model

BACKGROUND: Liarozole fumarate (liarozole – R85246) is a novel compound with characteristics of both aromatase inhibitor (AI) and a retinoic acid metabolism blocking agent (RAMBA). Our objective was to determine the effects of liarozole alone or in combination with tamoxifen on the N-methyl-N-nitros...

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Autors principals: Goss, Paul E, Strasser-Weippl, Kathrin, Qi, Shangle, Hu, Haiqing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796889/
https://ncbi.nlm.nih.gov/pubmed/17266767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-26
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