Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

OBJECTIVE: Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters (FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial injury and acute pancreatitis (AP). This study investigated the relative importance of oxidative and non-oxidative pathway...

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Detaylı Bibliyografya
Asıl Yazarlar: Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2014
Konular:
Pancreas
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112447/
https://ncbi.nlm.nih.gov/pubmed/24162590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304058
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