Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

OBJECTIVE: Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters (FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial injury and acute pancreatitis (AP). This study investigated the relative importance of oxidative and non-oxidative pathway...

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書誌詳細
主要な著者: Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2014
主題:
Pancreas
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112447/
https://ncbi.nlm.nih.gov/pubmed/24162590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304058
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