Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

OBJECTIVE: Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters (FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial injury and acute pancreatitis (AP). This study investigated the relative importance of oxidative and non-oxidative pathway...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2014
Teme:
Pancreas
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112447/
https://ncbi.nlm.nih.gov/pubmed/24162590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304058
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki