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Mutational and fitness landscapes of an RNA virus revealed through population sequencing
RNA viruses exist as genetically diverse populations(1). It is thought that diversity and genetic structure of viral populations determine the rapid adaptation observed in RNA viruses(2) and hence their pathogenesis(3). However, our understanding of the mechanisms underlying virus evolution has been...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111796/ https://ncbi.nlm.nih.gov/pubmed/24284629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12861 |
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