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Exploring the Fitness Landscape of an RNA Virus by Using a Universal Barcode Microarray
Studies of viral pathogenesis have relied heavily on analyses of specific clones and their genetic determinants of virulence. It is sometimes difficult to apply this reductionist approach to the study of RNA viruses, which by virtue of their very high mutation rates, exist as a complex mixture of mu...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126141/ https://ncbi.nlm.nih.gov/pubmed/21289109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02217-10 |
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