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RNA recombination enhances adaptability and is required for virus spread and virulence

Mutation and recombination are central processes driving microbial evolution. A high mutation rate fuels adaptation, but also generates deleterious mutations. Recombination between two different genomes may resolve this paradox, alleviating effects of clonal interference and purging deleterious muta...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Xiao, Yinghong, Rouzine, Igor M, Bianco, Simone, Acevedo, Ashley, Goldstein, Elizabeth Faul, Farkov, Mikhail, Brodsky, Leonid, Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840895/
https://ncbi.nlm.nih.gov/pubmed/27078068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.03.009
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