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Simultaneous determination of fludarabine and clofarabine in human plasma by LC-MS/MS

A method for quantification of fludarabine (FDB) and clofarabine (CFB) in human plasma was developed with an API5000 LC-MS/MS system. FDB and CFB were extracted from EDTA plasma samples by protein precipitation with trichloroacetic acid. Briefly, 50 µL plasma sample was mixed with 25 µL internal sta...

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Autors principals: Huang, Liusheng, Lizak, Patricia, Dvorak, Christopher C., Aweeka, Francesca, Long-Boyle, Janel
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110960/
https://ncbi.nlm.nih.gov/pubmed/24820973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.04.045
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