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Low Proportions of CD28(−) CD8(+) T cells Expressing CD57 Can Be Reversed by Early ART Initiation and Predict Mortality in Treated HIV Infection

Background. Unlike cytomegalovirus (CMV) infection and aging, human immunodeficiency virus (HIV) decreases the proportion of CD28(−)CD8(+) T cells expressing CD57. Whether this abnormality predicts mortality in treated HIV infection and can be reversed by early antiretroviral therapy (ART) remains u...

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Autors principals: Lee, Sulggi A., Sinclair, Elizabeth, Jain, Vivek, Huang, Yong, Epling, Lorrie, Van Natta, Mark, Meinert, Curtis L., Martin, Jeffrey N., McCune, Joseph M., Deeks, Steven G., Lederman, Michael M., Hecht, Frederick M., Hunt, Peter W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110459/
https://ncbi.nlm.nih.gov/pubmed/24585893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu109
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