Low Proportions of CD28(−) CD8(+) T cells Expressing CD57 Can Be Reversed by Early ART Initiation and Predict Mortality in Treated HIV Infection

Background. Unlike cytomegalovirus (CMV) infection and aging, human immunodeficiency virus (HIV) decreases the proportion of CD28(−)CD8(+) T cells expressing CD57. Whether this abnormality predicts mortality in treated HIV infection and can be reversed by early antiretroviral therapy (ART) remains u...

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Bibliographic Details
Main Authors: Lee, Sulggi A., Sinclair, Elizabeth, Jain, Vivek, Huang, Yong, Epling, Lorrie, Van Natta, Mark, Meinert, Curtis L., Martin, Jeffrey N., McCune, Joseph M., Deeks, Steven G., Lederman, Michael M., Hecht, Frederick M., Hunt, Peter W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110459/
https://ncbi.nlm.nih.gov/pubmed/24585893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu109
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