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Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging

BACKGROUND: Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase “immunosenesence” of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a marker of proliferative history. Whether chronic HIV infection causes similar effe...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Sulggi A., Sinclair, Elizabeth, Hatano, Hiroyu, Hsue, Priscilla Y., Epling, Lorrie, Hecht, Frederick M., Bangsberg, David R., Martin, Jeffrey N., McCune, Joseph M., Deeks, Steven G., Hunt, Peter W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937334/
https://ncbi.nlm.nih.gov/pubmed/24586783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089444
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