Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging

BACKGROUND: Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase “immunosenesence” of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a marker of proliferative history. Whether chronic HIV infection causes similar effe...

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Main Authors: Lee, Sulggi A., Sinclair, Elizabeth, Hatano, Hiroyu, Hsue, Priscilla Y., Epling, Lorrie, Hecht, Frederick M., Bangsberg, David R., Martin, Jeffrey N., McCune, Joseph M., Deeks, Steven G., Hunt, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937334/
https://ncbi.nlm.nih.gov/pubmed/24586783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089444
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