Antiretroviral Therapy Initiated Within 6 Months of HIV Infection Is Associated With Lower T-Cell Activation and Smaller HIV Reservoir Size

Background. CD4(+)/CD8(+) T-cell activation levels often remain elevated in chronic human immunodeficiency virus (HIV) infection despite initiation of antiretroviral therapy (ART). T-cell activation predicts early death and blunted CD4(+) T-cell recovery during ART and may affect persistent HIV rese...

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Detalhes bibliográficos
Main Authors: Jain, Vivek, Hartogensis, Wendy, Bacchetti, Peter, Hunt, Peter W., Hatano, Hiroyu, Sinclair, Elizabeth, Epling, Lorrie, Lee, Tzong-Hae, Busch, Michael P., McCune, Joseph M., Pilcher, Christopher D., Hecht, Frederick M., Deeks, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778965/
https://ncbi.nlm.nih.gov/pubmed/23852127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit311
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