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Differential effects of aging on dendritic spines in visual cortex and prefrontal cortex of the rhesus monkey

Aging decreases the density of spines and the proportion of thin spines in the non-human primate (NHP) dorsolateral prefrontal cortex (dlPFC). In this study, we used confocal imaging of dye-loaded neurons to expand upon previous results regarding the effects of aging on spine density and morphology...

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Bibliographic Details
Main Authors: Young, Megan E., Ohm, Daniel T., Dumitriu, Dani, Rapp, Peter R., Morrison, John H.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108992/
https://ncbi.nlm.nih.gov/pubmed/24853052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.05.008
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