Clinically Relevant Hormone Treatments Fail to Induce Spinogenesis in Prefrontal Cortex of Aged Female Rhesus Monkeys

Preclinical animal models have provided strong evidence that estrogen (E) therapy (ET) enhances cognition and induces spinogenesis in neuronal circuits. However, clinical studies have been inconsistent, with some studies revealing adverse effects of ET, including an increased risk of dementia. In an...

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Detalhes bibliográficos
Main Authors: Ohm, Daniel T., Bloss, Erik B., Janssen, William G., Dietz, Karen C., Wadsworth, Shannon, Lou, Wendy, Gee, Nancy A., Lasley, Bill L., Rapp, Peter R., Morrison, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657730/
https://ncbi.nlm.nih.gov/pubmed/22915112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1881-12.2012
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